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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DUOX2
All Species:
18.48
Human Site:
S698
Identified Species:
40.67
UniProt:
Q9NRD8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NRD8
NP_054799.4
1548
175364
S698
Q
Q
V
N
L
I
L
S
N
N
R
G
C
R
T
Chimpanzee
Pan troglodytes
XP_510367
1547
175357
S697
Q
Q
V
N
L
I
L
S
N
N
R
G
C
R
T
Rhesus Macaque
Macaca mulatta
XP_001103398
1377
155329
L613
C
C
L
P
L
V
S
L
L
L
S
G
V
V
A
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q9ES45
1517
171539
S698
Q
Q
V
N
L
I
L
S
S
S
H
G
R
R
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518643
1547
175433
S698
Q
Q
L
N
L
I
L
S
N
N
R
G
R
R
T
Chicken
Gallus gallus
XP_425053
1523
173782
S673
Q
S
V
E
V
I
L
S
S
N
K
G
N
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919394
1322
150039
D558
P
Q
P
I
R
A
S
D
L
Q
P
C
T
K
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VQH2
1475
170768
D661
T
F
S
L
K
H
I
D
V
V
S
V
E
E
S
Honey Bee
Apis mellifera
XP_624355
1492
172466
N676
T
F
D
F
N
D
V
N
T
V
T
M
E
E
S
Nematode Worm
Caenorhab. elegans
O61213
1497
170397
F683
G
I
L
R
K
I
R
F
E
T
G
Q
K
I
E
Sea Urchin
Strong. purpuratus
NP_001118237
1671
189876
S817
T
K
V
G
L
L
V
S
P
D
G
K
R
R
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
85.4
N.A.
N.A.
N.A.
82.6
N.A.
77.6
65.5
N.A.
45.5
N.A.
38.2
39.5
35.8
41.8
Protein Similarity:
100
99.2
86.3
N.A.
N.A.
N.A.
90.1
N.A.
85.5
79.1
N.A.
60.5
N.A.
58
60.3
55.6
59.7
P-Site Identity:
100
100
13.3
N.A.
N.A.
N.A.
73.3
N.A.
86.6
46.6
N.A.
6.6
N.A.
0
0
6.6
26.6
P-Site Similarity:
100
100
26.6
N.A.
N.A.
N.A.
86.6
N.A.
93.3
73.3
N.A.
13.3
N.A.
13.3
20
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
28
% A
% Cys:
10
10
0
0
0
0
0
0
0
0
0
10
19
0
0
% C
% Asp:
0
0
10
0
0
10
0
19
0
10
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
0
0
0
10
0
0
0
19
19
10
% E
% Phe:
0
19
0
10
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
0
0
0
0
19
55
0
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
10
0
10
0
55
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
19
0
0
0
0
0
10
10
10
19
0
% K
% Leu:
0
0
28
10
55
10
46
10
19
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
37
10
0
0
10
28
37
0
0
10
0
0
% N
% Pro:
10
0
10
10
0
0
0
0
10
0
10
0
0
0
0
% P
% Gln:
46
46
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
0
0
0
10
10
0
10
0
0
0
28
0
28
46
0
% R
% Ser:
0
10
10
0
0
0
19
55
19
10
19
0
0
0
19
% S
% Thr:
28
0
0
0
0
0
0
0
10
10
10
0
10
0
37
% T
% Val:
0
0
46
0
10
10
19
0
10
19
0
10
10
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _